Associate Director, Antibody Development

Company: NGM Biopharmaceuticals, Inc.
Location: South San Francisco
Posted on: May 3, 2021

Job Description:

NGM Biopharmaceuticals, Inc. is a biopharmaceutical company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases. Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to build a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine that has a track record of generating one new IND candidate per year. NGM's current pipeline of clinical-stage programs consists of five drug candidates targeting liver and metabolic diseases, retinal diseases and cancer. The most advanced drug candidate, aldafermin (NGM282), is in Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH) and is wholly-owned by NGM. Another drug candidate, NGM621, is in a Phase 2 study in geographic atrophy (GA) secondary to age-related macular degeneration (AMD). NGM's strategic collaboration with Merck, with a current term running to March 2022, provides us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates.

NGM is excited to hire a Ph.D. level scientist with expertise in antibody drug discovery and development to join our Biologics group. The ideal candidate will have already led a group of researchers to get an antibody candidate from discovery to the preclinical stage.

Responsibilities

• Lead a team of Researchers to discover and develop novel antibody therapeutics using hybridoma or display technologies
• Serve as a company-wide antibody subject matter expert; provide expertise and insight to guide antibody drug candidate selection and characterization
• Brainstorm with Biology researchers to generate innovative ideas using various antibody formats, such as bispecific/multispecific antibodies, antibody-protein fusions, etc.
• Participate in discussions with company leadership to set strategies for drug development and research directions
• Manage antibody discovery and engineering projects from research to pre-clinical stage
• Troubleshoot experimental techniques with team members
• Serve as a thought partner for researchers designing antibody-focused experiments
• Generally be on top of the Antibody field in terms of literature, technologies, and the competitive landscape

Qualifications

• Ph.D. in Biology/Biochemistry
• Direct experience in discovering or engineering at least one clinical stage antibody therapeutic
• Broad and deep experience in antibody discovery or engineering, which may include hybridoma, B cell technology, and/or display technologies
• Strong publication record
• Strong interpersonal, presentation, and communication skills

NGM offers a creative, collaborative, highly challenging scientific environment, along with a strong compensation package that includes salary, stock options, employee stock purchase program participation, 401(k) and a comprehensive, industry-leading, benefits package.

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Keywords: NGM Biopharmaceuticals, Inc., South San Francisco , Associate Director, Antibody Development, Other , South San Francisco, California