Amgen is a leading global biotechnology company, with a mission
to serve patients. As a science-based, patient-focused
organization, we discover and develop innovative therapeutics to
treat serious illness. Our medicines have made a dramatic
difference in the lives of millions.
We are seeking a scientist to join the Structural Biology
Department at our site in South San Francisco, CA. The Structural
Biology laboratory provides comprehensive molecular insights and
structure-based design for drug-target assessment, mechanism of
action, protein-protein and protein-ligand interactions, as well as
protein engineering to facilitate drug discovery across various
therapeutic areas. The scientist will be part of a growing
structure biology group and will be responsible for structure
determination of target molecules using X-ray crystallography
and/or cryo-electron microscopy. The candidate will be working
closely with molecular biologists and protein biochemists in the
protein expression group. The candidate will also interact directly
with both small molecule and large molecule scientists including
computational scientists, medicinal chemists, and protein
engineers. The candidate must be flexible to apply her/his
knowledge to new areas of study, with strong interpersonal and
communication skills to thrive in a highly collaborative
Doctorate degree with significant postdoc experience
Master's degree and 6 years of Structural Biology experience
- Ph.D with focus in Structural Biology
- Postdoc research experience in large macromolecular complexes
and/or membrane proteins.
- Knowledge of state-of-the-art protein structural biology
techniques including all aspects of construct design, expression,
purification, characterization, crystallization, structure
determination and analysis.
- Experience in single particle cryo-EM workflow including grid
freezing and screening, data collection and processing,
three-dimensional reconstruction and model building.
- Excellent presentation skills (written and oral) for effective
team-based communication of results.
- Ability to work independently and effectively within timelines
and to collaborate in a multidisciplinary environment.
- Skills in managing multiple projects and capability to
If you're seeking a career where you can truly make a difference
in the lives of others, a career where you can work at the absolute
forefront of biotechnology with the top minds in the field, you'll
find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers
innovative human therapeutics. Our medicines have helped millions
of patients in the fight against cancer, kidney disease, rheumatoid
arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life
for people around the world, Amgen fosters an inclusive environment
of diverse, ethical, committed and highly accomplished people who
respect each other but compete intensely to win. Together, we live
the Amgen values as we continue advancing science to serve
Amgen is an Equal Opportunity employer and will consider all
qualified applicants for employment without regard to race, color,
religion, sex, sexual orientation, gender identity, national
origin, protected veteran status, or disability status.
Amgen will consider for employment qualified applicants with
criminal histories in a manner consistent with the San Francisco
Fair Chance Ordinance.