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Company: Merck
Location: South San Francisco
Posted on: May 3, 2021

Job Description:

**Job Description**

Our company's Research Laboratories in South San Francisco is seeking a highly capable Senior Scientist with a strong background in biochemical/cellular pharmacology, assay development, and screening to join the Quantitative Biosciences department. The individual will work in the laboratory to independently design, execute, and interpret complex in vitro studies to support drug discovery across multiple therapeutic areas. Successful candidates should demonstrate broad scientific knowledge and technical expertise in pharmacology, a strong track record supporting drug discovery research, and the ability to leverage lab automation to improve efficiency and drive innovation. He or she should have excellent analytical and communication skills and can work effectively in a highly collaborative cross-functional team environment.

**Key responsibilities:**

+ Provide biochemical and cellular pharmacology expertise to support drug discovery across multiple therapeutic areas (cardiometabolic, immunology, and oncology)

+ Develop and implement potency, selectivity, and mechanistic assays to characterize diverse targets, molecules, and mechanism of actions, using sophisticated experimental methods

+ Leverage extensive lab automation to improve quality, efficiency, and overall productivity

+ Drive scientific and technical innovations to enhance functional capability and productivity

+ Represent Quantitative Biosciences department in multi-disciplinary project teams to provide robust scientific and technical support

+ Collaborate extensively across the our research laboratories network and with external partners to drive project progression toward milestones


+ Ph.D. in Pharmacology, Biochemistry, Cell Biology or a related scientific discipline, with a minimum of 3 years of drug discovery experience in a biotech/pharmaceutical setting

+ Relevant knowledge of mechanistic pharmacology and bioassay development, and strong expertise in SAR support for drug discovery

+ Highly skilled in the design and execution of high-throughput biochemical and cell assays, using a wide range of modern technologies and detection methods

+ Broad knowledge and hands-on experience with automated liquid handling instruments (Multidrop, Bravo, Echo, etc.) and integrated robotic systems for assay operation

+ Proven record of success in leveraging biochemical and cell assays for compound screening, pharmacological characterization, and lead optimization

+ Good working knowledge of cardiometabolic biology, immunology or oncology is a plus

+ Demonstrated ability to work collaboratively in a cross-functional environment to advance drug discovery, with excellent organization and communication skills

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

**Who we are ...**

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

**What we look for ...**

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue **Inventing For Life, Impacting Lives** while **Inspiring Your Career Growth** .





In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE ($1533/rel-task/3001$14.htmld)

Current Contingent Workers apply HERE ($4020.htmld)

**US and Puerto Rico Residents Only:**

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here ( []) if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster (

EEOC GINA Supplement

OFCCP EEO Supplement (

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

**Search Firm Representatives Please Read Carefully**

Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

**Employee Status:**




**VISA Sponsorship:**


**Travel Requirements:**

**Flexible Work Arrangements:**


**Valid Driving License:**

**Hazardous Material(s):**

**Number of Openings:**


**Requisition ID:** R102738

Keywords: Merck, South San Francisco , Scientist, Other , South San Francisco, California

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