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Sr. Scientist - Structural Biology

Company: Amgen Inc.
Location: South San Francisco
Posted on: June 7, 2021

Job Description:

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions.

The Amgen research laboratory provides comprehensive molecular insight and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various important therapeutic areas. The Scientist will be part of a growing structure biology group and will be responsible for designing and purifying target proteins for Cryo-Electron Microscopy and X-ray crystallography, data collection and resolution of complex molecular structures.

Preferred qualifications and major accountabilities associated with this role include:

  • Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, crystallization, structure determination and analysis.
  • Experience in single particle cryo-EM processes (including sample/grid preparation and screening, data collection and processing, three-dimensional reconstruction and model building)
  • Familiarity with Linux OS (install, configure and maintain) is a strong plus.
  • Excellent presentation skills (written and oral) that enhance team-based delivery of results
  • Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment
  • Skills in managing multiple projects and capability to prioritize
  • The ideal candidates should have Ph.D in structural biology with significant postdoc research experience in membrane proteins and/or large macromolecular complexes

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

Keywords: Amgen Inc., South San Francisco , Sr. Scientist - Structural Biology, Other , South San Francisco, California

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