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Software Engineer - Infrastructure

Company: Freenome
Location: South San Francisco
Posted on: June 7, 2021

Job Description:

About the Role

Freenome is looking for an experienced infrastructure engineer to help build a cloud-native machine learning platform for the world's largest multi-analyte cancer genomics dataset.

As an engineering-forward biotech company, we apply modern engineering practices to build reliable, maintainable, scalable, and secure production systems for our clinical lab and Computational and Molecular Research Scientists.

Our infrastructure team is a small group where you will help set the culture and build the systems that allow us to move fast without breaking things. This is an opportunity to do meaningful engineering work that will directly save lives.

We value:

  • Rapid iteration and tight feedback loops
  • Continual improvement rather than disruption
  • Technical simplicity and elegance
  • A focus on the larger goals
  • Mutual respect and blameless postmortems
  • A culture of diversity and inclusion

How you'll contribute:

  • Improving the reliability and scalability of our platform for genomic research in concert with the Software Engineers and Computational Scientists who depend on it daily
  • Planning for significant growth and scaling challenges as we transition from research to product development
  • Lending your expertise to design and code reviews
  • Anticipating technical scaling limits before we reach them
  • Continually improving our security posture
  • Reinforcing good development practices across the entire organization

What you'll bring:

  • 3+ years of experience with production infrastructure, automation, and monitoring
  • B.S. or M.S. in computer science or a related technical field, or comparable experience
  • Experience in analyzing and troubleshooting distributed systems
  • Software design and development expertise, especially in Python
  • Practical knowledge of Linux internals
  • A systematic problem-solving approach, coupled with effective communication skills and a sense of ownership and drive

Nice to Haves:

  • Machine learning and data science tools, such as TensorFlow, PyTorch, Jupyter, or Kubeflow
  • Systems programming languages such as Go, Rust, or modern C++
  • Kubernetes, including tools such as Helm or Flux
  • Docker and Linux containers
  • Production deployment automation tools, such as Terraform or Ansible
  • Large-scale and/or high-performance storage systems, such as PostgreSQL, MySQL, Redis, HBase, Spanner, or Cassandra
  • Microservices, service meshes, or distributed tracing
  • Security, encryption, and certificate management
  • Networking, firewalls, load balancers, and HTTP internals
  • Monitoring, alerting, logging, and tracing tools, such as Prometheus, fluentd, or Jaeger
  • Data pipelines, such as Kafka, Spark, Airflow, Argo, Beam, or Flink
  • Google Cloud Platform experience
  • Experience with software in a regulated environment
  • Genomics or bioinformatics background

About Freenome

Freenome is on a mission to empower everyone with the tools they need to detect, treat, and ultimately prevent cancer.

We have pioneered the most comprehensive multiomics platform for early cancer detection through a routine blood draw. By combining deep expertise in molecular biology with advanced computational biology and machine learning techniques to recognize disease-associated patterns among billions of circulating, cell-free biomarkers, we are developing simple and accurate blood tests for early cancer detection and integrating the actionable insights into health systems to operationalize a machine learning feedback loop between care and science.

Our recent $270 Million Series C brings our financing to over $500 million from investors, including; Bain Capital, Perceptive Advisors, RA Capital, Polaris Partners, Andreessen Horowitz, funds and accounts advised by T. Rowe Price Associates, Inc., GV (formerly Google Ventures), Roche Venture Fund, Kaiser Permanente Ventures, American Cancer Society's BrightEdge Ventures, Data Collective Venture Capital, Novartis and Verily Life Sciences.

Our Science

Freenome is building technology to advance the understanding of cancer through multiple analytes derived from blood. These signals include cell-free DNA, methylation of cell-free DNA, cell-free RNA, circulating proteins, and immune profiling derived from thousands of prospective samples. By developing novel statistical learning methods and applying them to integrate various -omics datasets, Freenome is a leader in modeling specific biological mechanisms to capture disease-dependent signatures, including gene expression, immune response, tumor burden, the tissue of origin, and 3D chromatin structure.

By building comprehensive discovery datasets and modeling critical biological systems, Freenome is learning what biological changes are present within the blood between a variety of different disease states, including cancer, autoimmune disorders, infections, drug response, and aging. The synthesis of Freenome's datasets, cross-functional technical expertise, and audacious mission to discover biological truth, we seek to improve the lives of millions through early detection and early treatment of disease.

Our Culture

Freenomers are technical, creative, visionary, grounded, empathetic, and passionate. We build teams around divergent expertise, allowing us to solve problems and ascertain opportunities in unique ways. Freenomers are some of the most talented experts in their fields, joining together to advance healthcare, one breakthrough at a time.

We value empathy, integrity, and trust in one another, and we respect the diverse perspectives of our colleagues and those we serve. We assume positive intent and give each other the benefit of the doubt with the firm belief that we are a team working toward the same objectives. We believe in empowering and supporting each other in a collaborative and dynamic environment.

What does a successful person look like at Freenome?

Those who thrive at Freenome prioritize, manage, and execute their own goals with ownership and alignment with those of the company. They embrace our values of empathy, integrity, striving for greatness, servant leadership, trust, and holding themselves and their team accountable to these values. They crave collaboration with brilliant minds from disparate fields of study and believe that hiring and mentorship are fundamental to our success. Above all, they welcome and provide constructive feedback and criticism, trusting in others' good intentions, and being secure in knowing that embracing mistakes is the best way to learn and grow. For those who pursue challenges, understudied problems, and want the opportunity to see their work impact the lives of millions of people affected by cancer every year, there's no better place to be than Freenome.

Freenome is proud to be an equal opportunity employer and we value diversity. Freenome does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status, or any other basis covered by appropriate law.

Keywords: Freenome, South San Francisco , Software Engineer - Infrastructure, Other , South San Francisco, California

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