Company: Charles River Laboratories, Inc.
Location: South San Francisco
Posted on: June 8, 2021
For 70 years, Charles River employees have worked together to
assist in the discovery, development and safe manufacture of new
drug therapies. When you join our family, you will have a
significant impact on the health and well-being of people across
the globe. Whether your background is in life sciences, finance,
IT, sales or another area, your skills will play an important role
in the work we perform. In return, well help you build a career
that you can feel passionate about.
We are seeking an experienced Director,
Immunologyfor our growingDiscoverysite
located inSouth San Francisco, CA.
At Distributed Bio, a Charles River Laboratory company, our
mission is to define a new paradigm in revolutionary bioengineered
medicines for the biotechnology industry. In monoclonal
therapeutics, our integration of computational immunology,
bioengineering and robotics has enabled us to create a pipeline of
molecules with unprecedented biophysical properties, while also
supporting all of our partners with developable antibodies against
any drug target of interest.
Our ability to discover antibodies against challenging pMHC,
pathogen toxin, GPCR and Ion Channel targets, as well as a novel
high-throughput discovery of CAR-T, has resulted in the growth of
our antibody discovery business.
We are seeking a candidate with relevant experience who possesses a
broad knowledge in the fields of immunology, molecular immunology
and antibody discovery. This position will lead a team driving the
experimental design and execution of research in antibody
discovery, cell biology, immunology, and assay development. Major
responsibilities will include working with internalteams and
external partners to define and interrogate relevant biology and
antibody mechanism of action, to enable lead candidate selection
with the goalof developing novel therapeutic approaches.
The following are minimum requirements related to
- Education: Ph.D. in Immunology, biochemistry and/or molecular
biologyor related discipline preferred. Track record of
publications and innovation.
- Experience: 10 years of laboratory experience in the contract
research industry or pharmaceutical environment. At least 2 years
- An equivalent combination of education and experience may be
accepted as a satisfactory substitute for the specific education
and experience listed above.
- Strong skills in cellular and molecular immunology, cancer
immunology, and flow cytometry techniques.
- Expertise in generating and maintaining cell lines and primary
immune cell cultures and antibody-related assays.
- Demonstrated ability to design and supervise all aspects of in
vitro and in vivo cancer immunotherapy models.
- Demonstrated ability to lead a team and supervise experienced
- Other: Ability to design and deliver novel solutions to
challening problems. Ability to critically evaluate written
scientific documents for overall quality, clarity of presentation,
and acceptability of scientific interpretation. Ability to handle
multiple projects, prioritize work and meet deadlines in fast paced
collaborative team environment. Excellent verbal and written
communication skills. Demonstrated independent analytical and
problem-solving abilities. Demonstrated proficiency in managing a
laboratory area. Demonstrated knowledge and full understanding of
regulatory requirements, site Standard Operating Procedures (SOPs),
company practices, and industry standards. Computer proficiency in
MS Word, Excel, Outlook.
Discovery from Charles River is industry-proven in the successful
development of novel therapies, with over 320 patents and 74
preclinical drug candidates delivered to our sponsors in the past
17 years. Backed by more than 650 scientists, our comprehensive,
integrated portfolio employs the latest technology and platforms to
provide chemistry, biology, and pharmacology services that support
clients from the earliest stages of hit identification all the way
through to IND. Our client-focused, collaborative approach creates
true partnerships that anticipate challenges, overcome obstacles,
and move us forward together on the journey of getting new drugs to
About Charles River
Charles River is an early-stage contract research organization
(CRO). We have built upon our foundation of laboratory animal
medicine and science to develop a diverse portfolio of discovery
and safety assessment services, both Good Laboratory Practice (GLP)
and non-GLP, to support clients from target identification through
preclinical development. Charles River also provides a suite of
products and services to support our clients clinical laboratory
testing needs and manufacturing activities. Utilizing this broad
portfolio of products and services enables our clients to create a
more flexible drug development model, which reduces their costs,
enhances their productivity and effectiveness to increase speed to
With over 13,000 employees within 80 facilities in 23 countries
around the globe, we are strategically positioned to coordinate
worldwide resources and apply multidisciplinary perspectives in
resolving our clients unique challenges. Our client base includes
global pharmaceutical companies, biotechnology companies,
government agencies and hospitals and academic institutions around
At Charles River, we are passionate about our role in improving
the quality of peoples lives. Our mission, our excellent science
and our strong sense of purpose guide us in all that we do, and we
approach each day with the knowledge that our work helps to improve
the health and well-being of many across the globe. We have proudly
supported the development of 80% of the drugs approved by the FDA
For more information, please visit www.criver.com.
Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer
Keywords: Charles River Laboratories, Inc., South San Francisco , Director, Immunology, Other , South San Francisco, California
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