Sr. Scientist - Cardiometabolic Research

Company: Amgen
Location: South San Francisco
Posted on: October 28, 2025

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Sr. Scientist - Cardiometabolic Research What you will do Lets do this. Lets change the world. In this vital role you will be at the forefront of ground breaking research, our Cardiometabolic Therapeutic Area team is dedicated to understanding the complexities of disease biology and discovering novel therapeutics. Youll collaborate with a team of world-class scientists, leveraging state-of-the-art technologies to make a real impact on patients' lives. As a Senior Scientist, you will: Design and perform laboratory-based assays to deepen our understanding of cardiometabolic disease biology Develop functional screening assays and evaluate potential therapeutics to advance the pre-clinical pipeline Organize and interpret data and present work to colleagues and project teams Contribute to the identification and validation of therapeutic targets Coordinate cross-functional efforts to achieve project goals and drive project advancement What we expect of you We are all different, yet we all use our unique contributions to serve patients. We are seeking a highly motivated scientist with excellent communication skills with the following qualifications: Basic Qualifications: Doctorate Degree (PhD) or Masters Degree with 3 years of experience or Bachelors Degree with 5 years of experience. Preferred Qualifications: Demonstrated expertise in the molecular mechanisms underlying cardiovascular disease biology. The successful candidate will have a strong record of high-impact publications in this field. Extensive experience in high-throughput cell-based and biochemical assays, including live cell imaging and image processing, qPCR, ddPCR, Western Blot, MSD, ELISA and flow-based expression analysis Hands-on expertise with cell line engineering technologies, including CRISPR and lentivirus, retrovirus-, or piggyBac-based stable cell line generation Experience with high-throughput functional perturbation approaches, including CRISPR-based or RNAi screens Experience with single-cell transcriptomics or other omics data for disease pathology and novel target identification What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, South San Francisco , Sr. Scientist - Cardiometabolic Research, Science, Research & Development , South San Francisco, California