Vice President or Senior Vice President, Clinical and Commercial Supply Chain

Company: IDEAYA Biosciences
Location: South San Francisco
Posted on: October 30, 2025

Job Description:

Non-Solicitation Policy and Notice to Agencies and Recruiters: IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships . Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences. All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to humanresources@ideayabio.com. We ask that you only email your interest once. Job Summary About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer. When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com. Location: South San Francisco, CA. Position Summary: IDEAYA Biosciences is seeking an experienced Vice President or Senior Vice President, Clinical and Commercial Drug Supply, to lead and execute the company’s operations and strategies to ensure clinical and commercial drug supply. This individual will bring to IDEAYA a proven track record of success and deep expertise in leading large-scale external commercial manufacturing, supply chain functions, ensuring reliable product quality, regulatory compliance, and on-time global supply. This role will be integral in IDEAYA’s transition to a commercial-stage biotechnology company and will have an initial focus on U.S. commercial manufacturing launch readiness of our lead program, Darovasertib in Uveal Melanoma (UM), and will continue supporting the global launch plans and product life-cycle management. This role reports to the Chief Executive Officer and is based in IDEAYA’s South San Francisco, California office, with an expectation to be in the office a minimum of 4 days a week. This role may be filled at the Vice President or Senior Vice President level, depending on the experience, leadership capabilities, and qualifications of the final candidate selected. Job Description What you’ll do: Develop and own the global supply strategy for clinical and commercial phases — including demand forecasting, capacity planning, buffer stocks, and supply continuity. Define and implement a Sales & Operations Planning (S&OP) process aligned with commercial, finance, regulatory, and manufacturing functions. Assess and manage supply risk (e.g., supplier capacity constraints, regulatory delays, geo-risks) and build risk mitigation plans (dual sourcing, safety stocks, alternate routes). Oversee supply of investigational products (IPs) for clinical trials, including packaging, labeling, distribution, and returns. Lead tech transfers (from clinical to commercial) and scale-up from pilot to commercial processes, ensuring continuity. Work with external CDMOs and logistics/3PL partners to ensure timely supply for trials and launches. Manage commercial-scale manufacturing supply chains, packaging, serialization, warehousing, and distribution. This includes people management responsibilities of the direct reports reporting to this position that are responsible for the clinical and commercial supply, and the program management. Ensure readiness for product launch: validation, qualification, capacity ramp, regulatory compliance (serialization, track & trace, import/export). Oversee inventory management, allocation, demand-supply balancing, replenishment, and trade compliance. Select, contract, qualify, and manage performance of CDMOs, CMOs, packaging, testing, and logistics vendors. Oversee adherence to service-level agreements (SLAs), quality metrics, audits, and change control management. Collaborate and partner with cross functional teams to include CMC, Regulatory, Quality, Manufacturing, Commercial, Finance, Legal, and Project Management teams to align supply with product strategy. Serve as a member of the program or portfolio leadership team; provide executive-level updates and risk escalations. Lead the supply organization: hiring, mentoring, performance management, and capability building. Drive process improvement, system upgrades (e.g., ERP, supply chain digitalization), metrics/KPIs, and continuous optimization. Ensure operations comply with GMP, GDP, global import/export regulation, serialization & traceability, and regulatory requirements. Lead or support regulatory submissions related to manufacturing, supply, serialization, and drug product changes (e.g. in CMC sections). Prepare for and manage regulatory audits or inspections relevant to drug supply and logistics. Responsible for updating the CEO, executive leadership team, and the board of directors on a regular basis the overall strategy and deliverables related to the clinical and commercial supply chain Requirements: Advanced Degree (Ph.D. preferred) in life sciences, chemistry, pharmaceutical sciences, engineering, pharmacy, chemical engineering, or related field Minimum 20 years’ experience in the biotechnology and pharmaceutical industry, with extensive experience in pharmaceutical/biotech operations, including clinical and commercial supply. Proven track record in successfully transitioning products from clinical to commercial stage. Demonstrated experience in supply chain management, CDMO/CMO oversight, technology transfers, vendor management, logistics, and serialization. Technical expertise, deep understanding, and strategic mindset of GMP regulations, quality systems, and global supply chain management. A strong understanding of CFR Parts 58, 210, and 211; ICH; and FDA regulatory guidance related to pharmaceutical development, manufacturing, and specifications is required Commercial-stage Subject Matter Expertise. Must display a strong leadership presence as a commercial-stage technical operations subject matter expert, driving continuous improvement initiatives and adeptly tackling complex commercial-stage supply chain challenges. Regulatory acumen and direct experience with global regulatory filings, inspections, and compliance standards, including authoring and reviewing Module 3 documentation Essential leadership skills and proven success in building and leading technical operations, multidisciplinary teams, high-performing cross-functional teams, managing complex projects, highly collaborative, strong teamwork and interpersonal skills, demonstrated strength in influencing at all levels of the organization and in a matrixed environment to influence and galvanize cross-functional teams (internally and externally) Total Rewards Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs. The expected salary range for the roleof the Vice President level is $299,000 - $370,000 and Senior Vice President level is $337,000 - $417,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process. The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization. IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

Keywords: IDEAYA Biosciences, South San Francisco , Vice President or Senior Vice President, Clinical and Commercial Supply Chain, Science, Research & Development , South San Francisco, California